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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0216c4294bfa56e0841c2cf6d5af7c0dbc9e17158da168ef568c2d1c11996656' 
  AND token = 'e0dDRGe980AghmOveDWG31h2FuH2zUOmRGu03fZ6BfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}