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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ce1ae2d1119c71e97a3f4a3badabf56015bfdaf47f5b687a4b5a173ece22e86' 
  AND token = 'O2Wl/HiYWLuzu5UzUtbed0gpU4IfVNeXN6E9r8Hyh+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}