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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '842ebed3bba143f024f7ef2170c80b45508a733c1dcc4132ef382a992f572a4d' 
  AND token = '1rHihEZ+FIlX/eqL9wednY6IJstkS4y2oOdjtTg+j8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}