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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581a2240a8052d863b37df839bba8f6b1a5973896f7d455c10301f5ac226d4be' 
  AND token = '7uVe43qkRDNtcSQT+r+anvUj1SDXq0g8mh1wPJAT4vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}