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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a16b37dd12a5b65eaf4060421548a4228d022e28d94c0bdc69b9ce9de084cb3' 
  AND token = 'ztXrp4KS6RLG9mcCb3f8jHh7aR/jTN3fSw17a7h3WiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}