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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '350ccb75cb510159e776a213fddf4c42dd48a03000d839709a3e0999ac770a39' 
  AND token = 'ue/sgVwwxF5dtpECzNgX3Vnx0eSemnl2lQ5z6PcRkJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}