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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23aec5902a5b0ad17f1481850052af9efde839be2f8e2c2c7d0097f767889bf1' 
  AND token = 'zMWKIDRudCFTRUT9vJo0bB80gkZD+ZSG4BxkY9yVsHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}