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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2711f2f8f82ff1bff48a29de2cebf562e1b4f73fc7bff018c0b8f5eb8b233c' 
  AND token = '1QrIkupaJkPT5fw3Srfq8I4clbCAyCEdOKbwCOe1TFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}