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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb8342940f3846ba829b05059f9394da36645ca5832415c0398afc0844b30aed' 
  AND token = 'QXZDiBa9YyD/pAwpKidg0UaTreArgls5+/n1K7ETs14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}