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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f734c5fd948e0d273c1a0404e215eb1771d66e75aa051d1044bb2c3de87503ef' 
  AND token = 'eWihFVfK/PPa5Pl0fgIZTv3Gu1P/Utn/afQdGZ2/cP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}