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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06328b4d8d8f10a530cdb8a81496f06aa9268775e9cd5bc9b6c6aee15c373061' 
  AND token = 'Gj/FdcLOwjYSeoeNUMwf0wpIAKJYwYR23+dd3OFGWe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}