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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9de05129ac887c09e77ecc9cb292b0b9d12f66f95822cae28910568b725ad1' 
  AND token = 'IJGzr56JVBmT71amjzEKL2yOoulX40GBfGPDuup/wqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}