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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '327c69f0167a76ff84887205a9a10e0c865789510b788eb3e494e2d5fe192452' 
  AND token = '05d+YUFZ0kwgevsQJqQPeM1EGIwtdHRwrla8d0XpFuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}