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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1189470ae91fc03e0f2578ccc92a46737601c67bb715c3f7de9bf1b52658ecad' 
  AND token = 'QuOoLxnJYZ8n4OzFyN89xDhBXRFn3IzySwnd0VMWWnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}