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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '981ae17496583c6ca4e5046e66517099998e4d4b1d8792507c09b3fdfff28ee3' 
  AND token = 'xyC0fLjUBtGcntpu63SxHoVFZewGwtI7oZTOTAMlz/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}