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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66e0dc9633bb541115ee0a97e12f2fc7beb92b89cb99461f60bb8b8a50c58042' 
  AND token = 'CWm7OGrZ/oGBYzHHDd4pUk4p41VtJ4VkRg39UZ8SoYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}