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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dedc26841ad78cc63284c90c3cd9cf3fb6ec67ea944f37f3b46fd1da50eeac81' 
  AND token = '+sagCOfjsfJYpWT1DVCUu8bS1fE7ChQavSfbJYZ40v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}