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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a08ce8a564e34faa4dbaff5794676f38e0a5ed8383bc5b6f87c2ab880af2020' 
  AND token = 'FiioQTC4gtLWy6ACNmVR+H9zfDnLnNz3IrPuh7Drkho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}