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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aa45bdb2a1f08ed244c10fb976bc34a3f2c5a4ce1963b01c2f28c0bb6b32bfa' 
  AND token = 'ZP25uDnnSWScNqCZh0NA6aKY3GTzbQgXv3c17qm1YDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}