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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2138ccb9f30c58be3d3f2ce63299c9e608949752786e93f83c02b19337c6f5' 
  AND token = 'HFzAuAYnm1/RvWb8rlW/CcS0qa7jXuAiyVI8LLmyHgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}