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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f42c230e0f465becee2b7b795809af9ce438baf45b7cdf9feb2a2ea73bd7b0c1' 
  AND token = 'UXt2sq4VRw//mQJWScj4PppC7vMLT5gv06XgWat33nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}