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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ce0bde468178a06e20f07e266b6554a134cb63516deafc1ce48d2b5880f6ee4' 
  AND token = 'DKeG0DX8tKnFmaknSKmzCLaekMcyioFTsClCUNb32c0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}