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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '736a4b66b9891f6773e902c08190b7bb53ca79dd2cbbc92a289b24b41caf9097' 
  AND token = 'UAKEoEKFjVeQQmDUAXD/PcIXNLJhuHm8o4B311YAlpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}