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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80567d2fbbbcd4e42085d2d38d13945255145f5f344908721432807520b29719' 
  AND token = 'nbEXV4rm9m1mMEJbMo7u6nu3AT5FDKJAluPuw+5LKE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}