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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ded412df284bf4846000ef10448039c83eb8314f34d84904521183eb858988' 
  AND token = 'YfJSlCg09AL5dqpOmsCwy1S4RRgyGsq7qZergsVqI9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}