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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22de9539128a850cf1b05081e8a8a5a5efc69be5f372ad6e5a93c0591b30898b' 
  AND token = '1t6u2XjmFFK0AKCXcYQwursbC94+RM+dPb4rR9TH7Fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}