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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e26c3e7d841e87dbc61a180e08bac3d3a7fc6921e45b4a7fd43180eb58ac7f75' 
  AND token = 'UZo5M7nL/U3Q8zdmxZs6MtGmzRDMVcF0oxmfMlxuut0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}