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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aedf906e1f8c78eadf1a1e293a004d49a554007b5f923f6a2f531fd199b43be' 
  AND token = 'DjQdvTwPs6b0+8M1Ri3Az8E8BpR4gJvq0FR/lE2myWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}