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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dabd84a616767eee51d1c882b81fd789e262f56025e1da73f692b19f5bf23e4' 
  AND token = 'HExHZxb5MvTpwsgoP5xpVOwhe9J7mz6nmqjyrWAC7sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}