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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '470adafba31ec2962ce86805bd01cf7d1b186110e421b86c38ea77c199397004' 
  AND token = '8eZ1ZjogKYjJeZ5GTzkzAJ7o1vmzEMs0vsP3YQeOIco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}