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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02f4e9bd426c490eada7b9ad6d2addbc9ca6df1a0175481c2bccacbf7c726867' 
  AND token = 'cOPUKiDJS6TrfSD5udLZ/E53XAZ8GmDf3mbMgWDa/Ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}