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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f9a95aca2a2b91814c11bae357c66e625c15b11a8512e8eb2c236e2154ef535' 
  AND token = 'G4aT7Fwur8wIDhIDK00Qsj8YEM0V298lk60k+qyUm1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}