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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de4c5db20d3df2c59374b254009e5e999fb2d67e5293b56a543e23296742e62' 
  AND token = 'NL4HDeKvi9Q+IgU4XfX/UtGPIiLG6falaRsqDbAZ5No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}