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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c43a2ff52ed59c3b450157af7bb5753059f599da79524b8cae23ff8fc10606' 
  AND token = '0CdQdxQ2nkf7q1iSMoRFGAW9jCy8G5fzcrN5ci8LgQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}