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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '789451e3a1aa3cc1c018acec267ce1493d7cc9b2ecbed2c7bc43dac2f4d17be8' 
  AND token = 'WN6RYyHrwyMevdUZ1g4iUbYiKku2DFV2nHMRTu2xkpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}