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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4875ab13f30a469bab729851f62a7cd02b58fb5347d4560f1c0e39684bae0521' 
  AND token = 'DEGfRvdYwxN8d1v2tjKFT5mRNnkIaBLaaYucAiZ9pvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}