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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a921248f020a5065e6a693433a3be0d81d02e18e653ababf5bc69095f968f752' 
  AND token = '3VemCEjC+Bw9m+H9yBhHLhgdo8QQzrvr8sdMOAjZ0QE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}