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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ee2f120684b1648f9e6dfffd333680e50f860ed04f0b289176d9377e1202f9' 
  AND token = 'tXM/49yRsHIk+ZHQmdPWRBStXbyQ6E2mgrONdgROm8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}