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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a0d2ad1b3ef2df30c3b5a30f153df40abf586f1817cec881de3c45b3e506683' 
  AND token = '27JjI97opBZOFhCya3LTXNm3kcCyMzUR/7K4hfs3HEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}