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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b18281001df2c17867fd71c873675dd7ac53ee36cd398bd04911350b5a4aa052' 
  AND token = 'DpGwRpdoenoxNIrV8k+egFYyv3yTboMix1/B3nbCir8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}