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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d658650de9e1e75fbffe255ede4d9512aa6328d22f46549a927eda1d22f747b' 
  AND token = 'V6PfmXUVLTOxcSemWg7Vqw9RbvRO9hdt89y22IFS5BY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}