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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88842e57c30b3fd605e239a6e12a2f8c29a43385b43cd141554fe9a89c05e771' 
  AND token = 'v6rsCQjc3Bm8NEZEnm+92Jik0SibrvZkx27CmhAXuWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}