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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adf6efd649471495fb14b8ea743c48d53d763d67576ac56e52ad500042fd36dd' 
  AND token = 'TGt2OgNDQ39z5UDWpbPOzKM1WxasR32GvqZmpQqnBDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}