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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e59ea6d79d50892471cba28ce303e851593f4211c0a6f728d00ed1291284d5bc' 
  AND token = 'zohtyHCEG1EZqVtfoH1NDQiY2M5Xpm1mksNrqpIm6R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}