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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b13a06cd1e0d4731d0d784ed003e372e106a18f03715e1026f1791bdf8a304' 
  AND token = 'CemRNI7DDvyuqi3qgNdQrks470oZ5+IJ9YhghQlRPO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}