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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a3501093458b07b078730be6df2186d018106c3d1a5197d7eae34ec44ebf298' 
  AND token = 'Wmsjfp7lx9QFUKk2COAz4Sh6a7x8k8sqhdbHpbDsHKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}