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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4177976917a129bd2bb6f58d5cf3da5b9e3989a8330a56554bc329797e0cf647' 
  AND token = 'dL0wlNyBrwIj3omry6j3foNx1ertqQB1+qvUuBCaFGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}