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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19afdc5c9ba2f1c994074fa2803663bb876b043a112dab6dbed1de27f54aa07f' 
  AND token = 'xe1tzid6RKu2yMRRtDhN5dRuNZFW3djPWjWxGNRJwK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}