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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ff552f456bf8ff3281b732e323ba0548bb61af9bfd7f18fb8fab6e10b4b679' 
  AND token = 'a81tnvAefRowUhp8Z+zN05/KgAp+ace0M1hCBE6LAHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}