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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4f12321adf12b0b8f780cccdceb60882e6d80f3f4c845e470d201b8a8d04859' 
  AND token = '1q9V5vu5le7VoyYVdwadd6zgQUH20fF0KBfrmZsD2MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}